Search results for "Reduced mobility"

showing 6 items of 6 documents

Detection and characterization of emerging psychoactive substances by ion mobility spectrometry

2014

Rapid detection and identification of novel psychoactive substances (NPS) continues to present significant analytical challenges to forensic and analytical chemists. Ion mobility spectrometry (IMS) has been traditionally considered as the analytical technique of choice to detect illicit drugs in security points in airports, borderlines and customs. Databases of the reduced mobility (K0 ) values of illicit drugs are available in the scientific literature and they should be completed with data of emerging designer drugs. In this paper, we have evaluated the effect of different measurement conditions and determined the K0 values of an important number of NPS including different families; such …

Chemistrymedicine.drug_classIon-mobility spectrometryAnalytical techniquePharmaceutical ScienceReduced mobilityPhenethylaminesRapid detectionAnalytical ChemistryCharacterization (materials science)Designer drugSynthetic cannabinoidsmedicineForensic engineeringEnvironmental ChemistryBiochemical engineeringSpectroscopymedicine.drugDrug Testing and Analysis
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Reduced mobility and physical activity as predictors of depressive symptoms among community-dwelling older adults: an eight-year follow-up study.

2003

Background and aims: Epidemiological research suggests that reduced physical activity and mobility may be associated with depressive symptoms. The present study examines the relative roles of mobility status and physical activity as predictors of depressive symptoms among community-dwelling older adults. Methods: The subjects comprised randomly selected, non-institutionalized residents of the city of Jyvaskyla, central Finland, born in 1904–1923. At baseline, 80% (N=1224) and after the 8-year follow-up period (1996) 88% (N=663) of eligible persons were interviewed. All non-institutionalized men and women (N=384) who participated in both baseline and follow-up interviews, who supplied data o…

GerontologyMaleAgingmedicine.medical_specialtyDepression scalePhysical activityWalkingMotor ActivityMobility statusEpidemiologymedicineElderly peopleHumansLife StyleDepressive symptomsAgedMovement DisordersDepressionFollow up studiesReduced mobilityPrognosisLogistic ModelsFemaleGeriatrics and GerontologyPsychologyFollow-Up StudiesAging clinical and experimental research
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Ion mobility spectrometry and high resolution mass-spectrometry as methodologies for rapid identification of the last generation of new psychoactive …

2018

A new drug trafficking trend has been observed in the last years by the introduction in the black market of new psychoactive substances (NPS) in order to difficult competent authority controls. In this study, ion mobility spectrometry (IMS) and high-resolution mass-spectrometry (HRMS) were proposed as vanguard and rearguard methodologies for the rapid identification of the last generation of NPS in seizures. The combined use of IMS and HRMS has been evaluated through the analysis of 24 NPS seized from 2016 to 2018 in Valencia (Spain) to demonstrate the utility of this approach. The characteristic reduced mobility (K0) values for seized NPS were determined and mass-mobility relationships wer…

Psychotropic DrugsChromatographyIon-mobility spectrometryChemistryChemistry Pharmaceutical010401 analytical chemistryOrganic ChemistryCombined useReduced mobility02 engineering and technologyGeneral MedicineDrug trafficking021001 nanoscience & nanotechnology01 natural sciencesBiochemistryMass Spectrometry0104 chemical sciencesAnalytical ChemistryRapid identificationSpainIon Mobility SpectrometrySynthetic cannabinoidsmedicine0210 nano-technologymedicine.drugJournal of Chromatography A
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Pertosylated polyaza[n](9,10)anthracenophanes

1997

Abstract Pertosylated polyaza[n](9,10)antracenophanes have been obtained in high yields by a modification of the Richman-Atkins methodology. Molecular Mechanics calculations as well as the crystal structure of the N,N′,N″,N‴-Tetratosyl-2,6,9,13-tetraaza[14](9,10)anthracenophane 4 derivative reveal the existence of a well defined cavity where both the aromatic moiety and the nitrogen donor atoms converge. Reduced mobility of the aliphatic chain is also observed as well as the presence of some strain at the benzylic positions.

StereochemistryOrganic Chemistrychemistry.chemical_elementReduced mobilityCrystal structureBiochemistryNitrogenchemistry.chemical_compoundCrystallographychemistryChain (algebraic topology)Drug DiscoveryAromatic moietyDerivative (chemistry)Tetrahedron
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Impact of COVID-19 pandemic on mobility in ten countries and associated perceived risk for all transport modes.

2021

The restrictive measures implemented in response to the COVID-19 pandemic have triggered sudden massive changes to travel behaviors of people all around the world. This study examines the individual mobility patterns for all transport modes (walk, bicycle, motorcycle, car driven alone, car driven in company, bus, subway, tram, train, airplane) before and during the restrictions adopted in ten countries on six continents: Australia, Brazil, China, Ghana, India, Iran, Italy, Norway, South Africa and the United States. This cross-country study also aims at understanding the predictors of protective behaviors related to the transport sector and COVID-19. Findings hinge upon an online survey con…

Viral DiseasesIndex (economics)EpidemiologySocial SciencesTransportationSurveysIran010501 environmental sciences01 natural sciencesGeographical LocationsMedical ConditionsEconomic inequalityRisk FactorsSurveys and QuestionnairesPandemicMedicine and Health SciencesPublic and Occupational Healthmedia_commonTravelMultidisciplinaryGeography05 social sciencesQRSocioeconomic Aspects of HealthInfectious DiseasesResearch DesignPublic transportRegression AnalysisEngineering and TechnologyMedicineResearch ArticleAsiaInequalityGeneral Science & Technologymedia_common.quotation_subjectScienceResearch and Analysis MethodsHuman Geography0502 economics and businessHumansPandemics0105 earth and related environmental sciences050210 logistics & transportationSurvey Researchbusiness.industryVDP::Technology: 500Individual mobilityCOVID-19Covid 19Health CareRisk perceptionMedical Risk FactorsPeople and PlacesEarth SciencesHuman MobilityTRIPS architectureDemographic economicscovid19 mobility restriction reduced mobility travel behaviours urban transport perceived riskBusinessPLoS ONE
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Hyaluronic Acid in the Treatment of Pain Due to Knee Joint Immobilisation

1995

This open, randomised study was carried out in order to evaluate the safety and efficacy of a course of 5 intra-articular injections (one per week) of hyaluronic acid (HA), administered to patients with pain and joint stiffness resulting from immobilisation of the knee in a plaster cast. The study was made in comparison with an untreated control group. 30 patients of both genders, aged between 18 and 65 years, immobilised in a plaster cast for at least 20 days and presenting with pain and reduced mobility, were included in the study. The results of the study show that, in comparison with the control group, treatment with HA produced a more rapid and effective reduction in pain and increase …

medicine.medical_specialtybusiness.industrySignificant differenceReduced mobilityGeneral MedicineKnee JointSurgerychemistry.chemical_compoundchemistryJoint mobilityUntreated controlJoint stiffnessHyaluronic acidmedicinePharmacology (medical)medicine.symptomAdverse effectbusinessClinical Drug Investigation
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